THE 2-MINUTE RULE FOR PHENOBARBITAL USAGE

Just after stopping a CYP3A4 inducer, since the effects of the inducer drop, the fentanyl plasma concentration will improve which could boost or prolong equally the therapeutic and adverse effects.Really serious - Use Alternative (one)fentanyl intranasal and phenobarbital equally enhance sedation. Avoid or Use Alternate Drug. Limit use to patients